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Vestibular Rehabilitation for Patient with Bilateral Peripheral Vestibular
Deficit
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Hyun Woo Park, Seong Ki Ahn
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Res Vestib Sci. 2016;15(1):1-4.
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 Abstract
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- Bilateral vestibular deficit affects far fewer patients than unilateral deficit, and
thus has been understudied. When bilateral vestibular organs are injured, loss of
input of vestibulo-ocular and vestibulo-spinal reflex that normally stabilize the
eyes and body, affected patients suffer blurred vision during head movement,
postural instability, and disequilibrium. Vestibular rehabilitation therapy is an
exercise-based treatment program designed to promote vestibular adaptation and
substitution. The rationale for the exercises, which originated from the observation
that patients who were active recovered faster, was based on the supposition that
the head movements that provoke the patient’s dizziness play an important role
in hastening the recovery process. Here the author reviews the clinical manifestation
and treatment of bilateral vestibular deficit that include vestibular
rehabilitation therapy and vestibular device that studied today.
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Immunohistochemical Study on β1- and β2-Adrenergic Receptors in Rat Vestibular Nuclei
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Seong Ki Ahn, Roza Khalmuratova, Dong Gu Hur, Ho Yeop Kim, Hyun Woo Park, Yeon Hee Joo, Hung Soo Kang
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Res Vestib Sci. 2012;11(2):59-63.
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Abstract
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- Background and Objectives: The aim of this study was to examine the localizations of β1- and β2-adrenergic receptors (ARs) in rat vestibular nuclei by immunohistochemical staining procedure.
Materials and Methods: Twelve male Sprague- Dawley rats were used in this study. Primary antibodies for the β1- and β2-ARs were used. The sections were treated with a biotinylated goat anti-rabbit antibody. The sections were then incubated in avidin-biotin-peroxidase reagent and processed with immunoperoxidase using 3.3’-diaminobenzidine tetrahydrochloride.
Results: β1-AR and β2-AR immunopositive neurons were found to be distributed throughout the four major vestibular nuclei. Both receptors were primarily detected in neuronal somata and their proximal dendrites. β1-AR and β2-AR were moderately expressed in the superior vestibular nucleus, lateral vestibular nucleus, medial vestibular nucleus, and spinal vestibular nucleus.
Conclusion: The present study demonstrates, for the first time, that β1-AR and β2-AR receptors are localized in rat vestibular nuclei. Furthermore, this study may provide additional speculation into the role of ARs during vestibular signal processing. Further studies are needed to clarify the roles played by β1-ARs and β2-ARs through physiologic and functional studies.
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A Case of Acute Serous Labyrinthitis Complicated by Chronic Otitis Media Showing Atypical Nystagmus Pattern
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Hyun Woo Park, Seong Ki Ahn, Dong Gu Hur
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Res Vestib Sci. 2011;10(1):42-45.
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Abstract
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- Serous or suppurative labyrinthitis is one of the intratemporal complications of acute or chronic otitis media. Labyrinthitis can occur by meningogenic or hematogenous infection. Major symptoms of labyrinthitis are vertigo and hearing loss. The disease progresses in two phases; serous labyrinthitis, so called toxic labyrinthitis, and suppurative labyrinthitis. If labyrinthitis treated at serous phase, hearing could be saved. But, if the disease progressed to suppurative phase, hearing loss is difficult to recover. Therefore it is very important to distinguish these two phases of labyrinthitis when treating the patient. In general, the direction of nystagmus during labyrinthitis is helpful sign to distinguish these two phases. We report here on an unusual case of acute serous labyrinthitis complicated with chronic otitis media showing atypical pattern with a review of the related literatures.
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KBS
