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Two Cases of Methyl Bromide Intoxication Mimicking Bickerstaff’s Brainstem Encephalitis
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Jin Young Seo, Byoung Soo Shin, Man Wook Seo, Young Hyun Kim, Sun Young Oh
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J Korean Bal Soc. 2008;7(2):199-203.
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Abstract
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- Background: Methyl bromide is toxic to the central and peripheral nervous systems. Two patients with occupational exposure to this agent are described.
Case: Two cases of previously healthy young men were involved. They had worked in a fumigating plant spraying fruits using methyl bromide for several months before admission. They showed general weakness, severe ataxia, bilateral dysmetria and bilateral lateral gaze limitation. And gaze-evoked nystagmus was observed in one of them. Brain MRI showed symmetrically increased signal intensity lesions including the brainstem, cerebellum and splenium of corpus callosum. After conservative treatment, they gradually improved over the next few weeks.
Conclusions: Symmetry and topography of our patients’ clinical and radiographic abnormalities support the proposal that methyl bromide exposure can produce symptoms similar to Bickerstaff’s brainstem encephalitis.
Key words: Methyl bromide, Acute intoxication, Bickerstaff’s brainstem encephalitis
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Two Cases of Congenital Ocular Motor Apraxia Associated With Cerebellar Vermian Dysplasia
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Jin Young Seo, Yeon Hee Lee, Byoung Soo Shin, Man Wook Seo, Young Hyun Kim, Sun Young Oh
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J Korean Bal Soc. 2008;7(1):63-67.
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Abstract
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- Congenital ocular motor apraxia is a rare syndrome characterized by rotational head thrusts that attempt to compensate for the lack of voluntary eye movements. We describe the clinical, oculographic and magnetic resonance imaging features of two children with congenital ocular motor apraxia.
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