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The Principle and Methodology of Vestibular Evoked Myogenic Potential
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Min Young Lee, Myung Whan Suh
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Res Vestib Sci. 2015;14(1):9-14.
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 Abstract
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- Vestibular evoked myogenic potential (VEMP) has developed as a broadly
applied vestibular function test in clinics from its introduction in 1992. In the
past, there was only one well known VEMP protocol, which is cervical VEMP,
however recently ocular VEMP is also popular. Therefore, clarifying the VEMP
recording protocol (cervical VEMP or ocular VEMP) before discussing the VEMP
result
has become essential. There is considerable difference regarding this VEMP
test from other vestibular function tests. VEMP is thought to be assessing the
functions of the otolith organs (utricle and saccule) which are evoked by acoustic
stimulus. Cervical VEMP is valuable since this is the only available test method
which could speculate the function of the saccule and inferior vestibular nerve.
Still, there’s less clearly understood part regarding the central pathway of VEMP.
However, many clinicians and researchers participating in vestibular research
speculate that this functional test will have a more dominant role in the near
future. Here we describe the basic principles and methodological considerations
regarding VEMP recording.
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A Case of Bilateral Benign Paroxysmal Positional Vertigo in Bilateral Mondini Malformation With Right Enlarged Vestibular Aqueduct Syndrome
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Min Young Lee, Sung Do Jung, Myung Whan Suh, Jae Yun Jung
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Res Vestib Sci. 2012;11(2):77-80.
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Abstract
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- Enlarged vestibular aqueduct syndrome (EVAS) is well known congenital bony ear anomaly. It’s audiologic symptoms and radiological findings are reported in many literatures. However vestibular symptoms of EVAS are rarely reported. A patient with right EVAS developed sudden spinning vertigo on casual observation. He is diagnosed as bilateral benign paroxysmal positional vertigo and recovered by canal repositioning maneuver. We present this case with reviews of previous literatures.
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Correlation between Spontaneous Nystagmus and Vestibular Function Test Parameters according to Gender and Age in Vestibular Neuritis
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Jae Yun Jung, Eun Seok Lim, Young Saeng Kim, Min Young Lee, Yong Won Chung, Chung Ku Rhee
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J Korean Bal Soc. 2006;5(2):248-252.
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Abstract
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- Background
and Objectives: There are caloric test, SCEP, DP in Step velocity and VOR asymmetry in SHA test as parameters for evaluation in unilateral peripheral vestibulopathy in parameter of vestibular function test. The aim of this study is to assess the correlation between these parameters and intensity of spontaneous nystagmus in vestibular neuritis.
Materials and Method: We evaluated 75 patients who were diagnosed as vestibular neuritis with 3 degree spontaneous nystagmus at vestibular function test lab from January 2000 to July 2005 in Dankook university hospital. The correlations between direction and intensity of spontaneous nystagmus and monothermal caloric test, SCEP and DP in step velocity, VOR asymmetry (0.01, 0.04, 0.16 Hz) in SHA test were analysed. And correlations according to sex, age were also analysed.
Results
The correlation coefficient between intensity of spontaneous nystagmus and monothermal caloric test was 0.60. The correlation coefficient between intensity of spontaneous nystagmus and SCEP was 0.35. The correlation coefficient between intensity of spontaneous nystagmus and Tc DP was 0.36 and it showed no significant correlation. The correlation coefficient between intensity of spontaneous nystagmus and VOR asymmetry (0.01, 0.04, 0.16) was 0.57, 0.46, 0.51, respectively and there was higher correlation in man, age under 60.
Conclusion
Intensity of spontaneous nystagmus showed close relations to monothermal caloric test, VOR asymmetry of SHA, Tc DP, SCEP DP in sequence. In addition, young male patients tends to be closely related to intensity of spontaneous nystagmus.
Key Words : Spontaneous nystagmus, Vestibular function test, Vestibular neuritis
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A Promotive Effect of Low Level Laser on Hair Cell Viability in Postnatal Organotypic Culture of Rat Utricles
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Yong Won Chung, Jin Chul Ahn, Eun Seok Lim, Young Saeng Kim, Min Young Lee, Jae Yun Jung, Chung Ku Rhee
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J Korean Bal Soc. 2006;5(1):29-34.
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Abstract
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- Background
and Objectives: To culture and maintain mammalian hair cells is still a big challenge. In this study, long-term organotypic culture of rat utricular maculae was established to study vestibular hair cell. The effects of low level laser on hair cell viability in postnatal organotypic culture of rat utricles were investigated.
Materials and Method: Uticular explants were prepared from postnatal 2 to 7 rats and cultured. To improve hair cell survival, the utricles were irradiated daily with low level laser. Whole-mount utricles were stained with FM1-43 which is known to be an efficient marker to identify live hair cells in cultured tissues. Such cells visualized directly through tissue culture dish with cover glass bottom by Confocal laser scanning microscope at specific time points.
Results
The explanted utricular hair cells were cultured for up to 31 days in in vitro culture system. In low level laser irradiation group, utricular hair cells were more survived at 24 DIV and 31 DIV.
Conclusion
These results suggest that low level laser promotes hair cell viability in utricular explants.
Key Words : Organotypic culture, Low level laser, FM 1-43, Utricle
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