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Volume 3 (1); June 2004
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Symposiums
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Basics of Eye Movements and Nystagmus
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Tae-Kyeong Lee, M.D.
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J Korean Bal Soc. 2004;3(1):7-24.
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Nystagmus in Peripheral Vestibular Disease
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Seung-Chul Lee, M.D.
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J Korean Bal Soc. 2004;3(1):32-35.
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Central Nystagmus
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Kwang-Dong Choi, M.D
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J Korean Bal Soc. 2004;3(1):36-45.
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Abstract
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Other Nystagmus
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Ki-Bum Sung, M.D., P
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J Korean Bal Soc. 2004;3(1):46-56.
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Abstract
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Diagnostic Approach to Dizziness
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Chung-Ku Rhee, M.D.1
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J Korean Bal Soc. 2004;3(1):59-63.
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Abstract
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Benign Paroxysmal Positional Vertigo
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Gyu Cheol Han, M.D.1
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J Korean Bal Soc. 2004;3(1):64-74.
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Meniere's Disease
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Kyu Sung Kim, M.D.
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J Korean Bal Soc. 2004;3(1):75-87.
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Dizziness of Vestibular Nerve Disorder
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Ja-Won Koo, M.D.1
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J Korean Bal Soc. 2004;3(1):88-94.
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Original Articles
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Drug Delivery System in Meniere's Disease
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Hiroshi Yamashita
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J Korean Bal Soc. 2004;3(1):125-126.
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Reviews
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Central Positional Nystagmus from Focal Brain Lesion
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Ja Won Koo, Kwang Dong Choi, So Young Moon, Seong Ho Park, Ji Soo Kim
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J Korean Bal Soc. 2004;3(1):129-135.
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Abstract
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- Department of Otolaryngology, Head and Neck Surgery1, and Neurology2, Seoul National University Bundang Hospital,
Seoul National University College of Medicine, Seongnam, Korea
Background and Objectives : Central positional nystagmus is induced by positional changes from brainstem or
cerebellar lesions. Differentiation central from peripheral positional nystagmus is important in clinical practice. To
delineate characteristics of the positional nystagmus observed in central lesions, we analyzed the parameters of
positional nystagmus from focal brain lesions.
Materials and Methods : Ten patients with central positional nystagmus were recruited from the dizziness clinic
of Seoul National University Bundang Hospital. All the patients had focal brainstem or cerebellar lesions documented
by magnetic resonance imaging. The nystagmus was observed with and without fixation by using Frenzel glasses or
Video Goggles. The nystagmus was videotaped or recorded with video-oculography. Provoking positional maneuvers,
direction, latency, duration, phase reversal, and fatigue phenomenon of the nystagmus were analyzed.
Results
: Of the 10 patients, seven had infarctions in the lateral medulla or inferior cerebellum while two
experienced cerebellar hemorrhage and remaining one showed a compression of the ventrolateral medulla by cavernous
malformation of the vertebral artery. The directions of the positional nystagmus were variable depending on the lesions
and provoking maneuvers. Most patients exhibited direction-changing nystagmus without latency, direction-reversal and
fatigue phenomenon. However, some of the patients also showed patterns of nystagmus characteristic of peripheral
positional nystagmus. In two of the four patients with infarction in the territory of medial posterior inferior cerebellar
artery, the positional nystagmus was the only abnormal findings.
Conclusions
: Central positional nystagmus may share many characteristics with peripheral type of positional
nystagmus. In individual cases, the patterns of nystagmus should be interpreted with caution in differentiating central
from peripheral positional nystagmus. Considering the isolated positional nystagmus in some patients with caudal
cerebellar lesions, systematic positional maneuvers should be applied to all the patients with vertigo
Key Words : Positional nystagmus, Medulla, Cerebellum
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Recurrent Episodic Vertigo Controlled by Phenytoin Sodium
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Chung Ku Rhee, Yong Won Chung, Ji Sun Kim, Joon Sik Yoon, Yang Hee Oh
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J Korean Bal Soc. 2004;3(1):136-140.
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Abstract
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- Background
: Many patients with symptom of recurrent episodic vertigo can neither be diagnosed nor treated. The
purpose of this study is to review clinical features of a group of patients with recurrent episodic vertigo that is not
defined to specific diagnosis of vertigo and to test the effectiveness of phenytoin sodium in the patients.
Method
& Material : 11 of 32 patients with recurrent vertigo not defined to specific diagnostic category of vertigo
who visited dizziness center of a tertiary care university hospital from November 1995 to April 2004 were studied. The
patient's charts were reviewed retrospectively. A thorough otolaryngologic and neurotologic evaluation was performed
in every case to determine the specific cause of dizziness. Vestibular function test, hearing test, magnetic resonance
imaging of brain, electroencephalogram, and 24 hour Holter EKG monitoring were performed in all cases. Consultations
to psychiatrist and neurologist were obtained. All patients were treated with phenytoin sodium.
Result
: The results of the vestibular function test, audiogram, MRI of brain, electroencephalogram, 24-hr holter
monitoring were normal. Any definitive diagnosis could not be reached to this group. Vertigo was controlled by
phenytoin sodium in all 11 cases.
Conclusion
: We report a group of patients with recurrent episodic vertigo that is not defined to any specific
diagnosis of vertigo. The vertigo symptom was controlled successfully by phenytoin sodium. This patients were
diagnosed as benign episodic vertigo as a separate disease entity.
Key Words : Vertigo, Phenytoin sodium, Episodic