A wide variety of abnormalities, both primary to the nerve itself and secondarily involving the nerve, can cause isolated abducens nerve palsy. Skull base lesions are also regarded as possible causes of isolated abducens nerve palsy but clival metastasis from systemic malignancy has rarely been reported. We report a case of isolated abducens nerve palsy caused by clival metastasis from rectal cancer. Key Words : Abducens nerve palsy, Metastasis, Skull base, Rectal neoplasm