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Research in Vestibular Science > Volume 15(1); 2016 > Article
Research in Vestibular Science 2016;15(1): 5-10.
신경이과 영역에서의 기능적 신경 영상 연구 기법
송재진
서울대학교 의과대학 분당서울대학교병원 이비인후과학교실
Functional Neuroimaging in Neuro-Otology
Jae Jin Song
Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea. jjsong96@snubh.org
ABSTRACT
Neuro-otologic symptoms such as dizziness, hearing loss, or tinnitus give rise to peripheral change-induced neuroplasticity or central pathology-induced structural or functional changes. In this regard, functional neuroimaging modalities such as positron emission tomography (PET), functional magnetic resonance imaging (fMRI), magnetoencephalography (MEG), quantitative electroencephalography (qEEG), or functional near infrared spectroscopy have provided researchers with possibility to observe neuro-otologic disease-induced central functional changes. Among these methods, PET and fMRI are advantageous over qEEG or MEG with regard to spatial resolution, while qEEG and MEG are advantageous over PET or fMRI with regard to temporal resolution. Also, fMRI or MEG is not suitable for patients with implanted devices, whereas PET is not ideal for repetitive measures due to radiation hazard. In other words, as these modalities are complementary to one another, researchers should choose optimum imaging modality on a case by case basis. Hereinafter, representative functional neuroimaging modalities and their application to neuro-otologic research will be summarized.
Keywords: Functional neuroimaging; Positron emission tomography; Functional magnetic resonance imaging; Magnetoencephalography; Electroencephalography
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