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5 Cerebellar ataxia, Neuropathy, Vestibular Areflexia Syndrome (CANVAS) 환자에서 뇌 대사감소
Byoung-Min Jeong1, Byoung-Soo Shin1, Man-Wook Seo1, Ji-Yun Park2, Hwan-Jeong Jeong3, Sun-Young Oh1

DOI: https://doi.org/ [Accepted]
Published online: November 29, 2017
1Department of Neurology, Chonbuk National University Medical School , Jeon-ju city, Korea
2Department of Neurology, Ulsan University Hospital , Ulsan city, Korea
3Department of Nuclear Medicine, Chonbuk National University Medical school, Jeoj-ju city, Korea
Corresponding author:  Sun-Young Oh, Tel: 063-250-1590, Fax: 063-251-9363, 
Email: ohsun@jbnu.ac.kr
Received: 4 November 2017   • Accepted: 29 November 2017
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Cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS) is a slowing progressive ataxic disorder characterized by bilateral vestibulopathy, cerebellar ataxia and somatosensory impairment. Autonomic dysfunction is recently considered as a core feature in CANVAS in addition to these symptoms. In most cases, patients with CANVAS show cerebellar atrophy in brain imaging, but some cases show minimal or no atrophy of cerebellum. Brain 18F-FDG PET study can be a complimentary tool to diagnosis CANVAS in cases of no structural abnormality such as cerebellar atrophy. Hereby, we present a case of CANVAS with minimal atrophy of cerebellum but showing a prominent hypometabolism in cerebellum, thalamus and posterior cingulate cortex in 18F-FDG PET.


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