소뇌교뇌각 신경초종을 동반한 Brun 안진

Brun’s Nystagmus with Cerebellopontine Angle Schwannoma

Article information

Res Vestib Sci. 2023;22(2):57-58

Publication date (electronic) : 2023 June 15

doi : https://doi.org/10.21790/rvs.2023.22.2.57

Seulgi Hong , Ji-Yun Park

, Seungjin Choi , Min Jee Kim

Department of Neurology, Ulsan University Hospital, Ulsan University College of Medicine, Ulsan, Korea

홍슬기, 박지윤

, 최승진, 김민지

울산대학교 의과대학 울산대학교병원 신경과학교실

Corresponding Author: Ji-Yun Park Department of Neurology, Ulsan University Hospital, Ulsan University College of Medicine, 877 Bangeojinsunhwando-ro, Dong-gu, Ulsan 44033, Korea Tel: +82-32-621-6475, Fax: +82-52-250-7088, E-mail: lullu21@hanmail.net; bingbing@uuh.ulsan.kr

Received 2023 June 1; Revised 2023 June 2; Accepted 2023 June 3.

A 70-year-old woman with trigeminal cystic schwannoma developed imbalance and dizziness over a year and a half. Neurologic examination revealed mild abduction limitation of the right eye and positive head impulse test toward the rightward and right peripheral facial palsy.

Videooculography showed a large-amplitude right-beating nystagmus with the rightward gaze and a small-amplitude left-beating nystagmus with the leftward gaze (Supplementary Video 1). Brain magnetic resonance imaging with enhancement demonstrated a well-defined huge mass (about 7×4 cm) in the right cerebellopontine angle compressing the middle cerebellar peduncle and pons (Fig. 1).

Fig. 1.

Brain magnetic resonance imaging with enhancement demonstrated a well-defined huge mass (about 7×4 cm) in the right cerebellopontine angle compressing the middle cerebellar peduncle and pons. The mass is high signal intensity on the T2-weighted image (A) and low signal intensity with mild ring enhancement on the T1-weighted images (B, C).

Brun’s nystagmus is a combination of ipsilesional gaze-evoked nystagmus with decreasing velocity waveform and contralesional gaze-induced vestibular nystagmus with linear velocity waveform [1]. The ipsilesional large-amplitude slow nystagmus is the result of impairment of gaze holding due to compression or ischemia of the horizontal neural integrator [2]. The contralesional small-amplitude fast nystagmus is caused by the impairment of the ipsilateral vestibular system. Since this rare directional changing nystagmus indicates localization and lateralization of a lesion, we must know the clinical meaning of this.

Notes

CONFLICT OF INTEREST

Ji-Yun Park is the Editor-in-Chief of Research in Vestibular Science and was not involved in the review process of this article. All authors have no other conflicts of interest to declare.

FUNDING/SUPPORT

None.

AUTHOR CONTRIBUTIONS

Conceptualization: SGH, JYP; Data curation: SGH; Formal analysis: SGH, JYP; Investigation: SGH; Methodology: JYP; Project administration: SJC, MJK; Supervision : SGH, JYP; Visualization: SJC, MJK; Writing–Original Draft: SGH, JYP; Writing–Review & Editing: All authors.

All authors read and approved the final manuscript.

SUPPLEMENTARY MATERIALS

Supplementary Video 1 can be found via https://doi.org/10.21790/rvs.2023.22.2.57. Videooculography showed a largeamplitude right-beating nystagmus with the rightward gaze and a small-amplitude left-beating nystagmus with the leftward gaze. Written informed consent was obtained for publication of this report and accompanying video.

rvs-22-2-57-Supplementary-Video-1.mp4

References

1. Leigh RJ, Zee D S. The neurology of eye movements. 5th ed. Oxford (UK): Oxford University Press; 2015.

2. Mantokoudis G, Korda A, Zee D S, Zamaro E, Sauter TC, Wagner F, et al. Bruns' nystagmus revisited: a sign of stroke in patients with the acute vestibular syndrome. Eur J Neurol 2021;28:2971–9.

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